CHEN yiyang

1. Basic information:

CHEN Yiyang, Ph. D., Lecturer.

2. Education and Work Experiences:

Sep. 2021 - now:  Lecturer, College of Veterinary Medicine, NWAFU, China

Dec. 2019 - Sep. 2021Postdoctor, College of Animal Science and Technology, NWAFU, China

Sep. 2016 - Dec. 2019 Ph. D. (Preventive Veterinary Medicine), College of Veterinary Medicine, NWAFU, China

Sep. 2013- Jun. 2016 Master (Preventive Veterinary Medicine), College of Veterinary Medicine, NWAFU, China

Sep. 2009 - Jun. 2013 Bachelor (Veterinary Medicine), College of Animal Science and Technology, Hainan University, China

3. Major Research Interests:

Basic research in veterinary molecular etiology and immunology, i. e., study on the antiviral mechanism of neutralizing antibodies of zoonotic hepatitis E virus; the third generation of genetic engineering antibody (nanobody) has been applied to the novel diagnostic technology and medicinal molecules.

4. Publications

(1) Baoyuan Liu^#, Yiyang Chen^#, Meimei Zhang, Tianxiang Chen, Yuan Zhang, Dan-Ba-Zha-Xi, Shixuan Xu, Qin Zhao, En-Min Zhou*; Identification and pathogenicity of hepatitis E virus from laboratory Bama miniature pigs, BMC Veterinary Research, 2022, 18(1).

(2) Yiyang Chen, Tianxiang Chen, Yuhang Luo, Jie Fan, Meimei Zhang, Qin Zhao, Yuchen Nan, Baoyuan Liu and En-Min Zhou. Synthetic peptides containing three neutralizing epitopes of genotype 4 swine hepatitis E virus (HEV) ORF2 induced protection against swine HEV infection in rabbit. Vaccines. 2020 Apr 13;8(2):178. doi: 10.3390/vaccines8020178.

(3) Liu, Baoyuan^#; Chen, Yiyang^#; Zhao, Liang; Zhang, Meimei; Ren, Xiaolei; Zhang, Yuan; Zhang, Beibei; Fan, Mengnan; Zhao, Qin; Zhou, En-Min*; Identification and pathogenicity of a novel genotype avian hepatitis E virus from silkie fowl (gallus gallus), Vet Microbiol, 2020, 245(0): 0-108688.

(4) Yiyang Chen^#, Baoyuan Liu^#, Yani Sun, Huixia Li, Taofeng Du, Yuchen Nan, Gaiping Zhang, Julian A. Hiscox,d En-Min Zhou, Qin Zhao, Characterization of Three Novel Linear Neutralizing B-cell Epitopes in the Capsid Protein of Swine Hepatitis E Virus. J. Virol. doi:10.1128/JVI.00251-18, 18 April 2018.

(5) Liu, Baoyuan^#; Chen, Yiyang^#, Sun, Yani., Nan, Yuchen., Li, Huixia., Du, Taofeng., Hiscox, J.A., Zhao, Qin., Zhou, EnMin., 2019. Experimental infection of rabbit with swine-derived hepatitis E virus genotype 4. Vet Microbiol. 229, 168-175

5. Major research projects:

(1) Chinese Universities Scientific Fund, Identification and functional study of host cell proteins attached by genotype 4 Hepatitis E Virus, 2022-2025, 200,000 RMB Yuan, project leader.

(2) National Natural Science Foundation of China, Mechanism in infection, replication and pathogenicity of animal hepatitis E virus cross-species infection, 2018-2022, 2.3 million RMB Yuan, participant.

6. Contact:

College of Veterinary Medicine, NWAFU, Xinong Road 22, Yangling, 712100, Shaanxi, China

Email: chenyiyang@nwsuaf.edu.cn

TEL:18829786066