LIU baoyuan
1. Basic information:
LIU Baoyuan, Ph. D., Lecturer.
2. Education and Work Experiences:
Jun. 2019 - now: Lecturer, College of Veterinary Medicine, NWAFU, China
Aug. 2017 -Jun. 2019Postdoctor, College of Life Sciences, NWAFU, China
Sep. 2012 -Jun. 2017 Ph. D. (Preventive Veterinary Medicine), College of Veterinary Medicine, NWAFU, China
Sep. 2009 - Jun. 2012 Master (Preventive Veterinary Medicine), College of Veterinary Medicine, Gansu Agricultural University, China
Sep. 2005 - Jun. 2009 Bachelor (Veterinary Medicine), College of Life Science and Engineering, Northwest Minzu University, China
3. Major Research Interests:
Basic research in molecular etiology and immunology, i. e., study on the pathogenicity and cross-species infection of hepatitis E virus; the third generation of genetic engineering antibody (nanobody) has been applied to the novel diagnostic technology and antiviral research of important animal diseases, such as hepatitis E and Porcine circovirus associated diseases.
4. Publications
(1) . Liu BY, Zhou EM, et al. Identification and pathogenicity of hepatitis E Virus from laboratory Bama miniature pigs. BMC Veterinary Research, 2022, 18(1).
(2) . Liu BY, Zhou EM, et al. Identification and pathogenicity of a novel genotype avian hepatitis E virus from silkie fowl (gallus gallus). Veterinary Microbiology, 2020, 245(0).
(3) . Chen YY, Liu BY (corresponding author), Zhou EM, et al. Synthetic Peptides Containing Three Neutralizing Epitopes of Genotype 4 Swine Hepatitis E Virus ORF2 induced Protection against Swine HEV Infection in Rabbit. Vaccines, 2020, 8(2).
(4) . Liu BY, Zhou EM, et al. Experimental infection of rabbit with swine-derived hepatitis E virus genotype 4. Veterinary Microbiology, 2019, 229:168-175.
(5) . Liu BY, Zhou EM, et al. Avian hepatitis E virus infection of duck, goose, and rabbit in northwest China. Emerging microbes & infections, 2018, 7(1):76.
(6) . Chen YY, Liu BY (co-first author), Zhou EM, et al. Characterization of Three Novel Linear Neutralizing B-Cell Epitopes in the Capsid Protein of Swine Hepatitis E Virus. Journal of virology, 2018, 92(13).
(7) . Liu BY, Zhou EM, et al. Effect of housing arrangement on fecal-oral transmission of avian hepatitis E virus in chicken flocks. BMC Veterinary Research, 2017, 13:282.
(8) . Zhao Q, Liu BY (co-first author), Zhou EM, et al. Decreased egg production in laying hens associated with infection with genotype 3 avian hepatitis E virus strain from China. Veterinary Microbiology, 2017, 203:174-180.
(9) . Liu BY, Zhou EM, et al. Rabbit hepatitis E virus is an opportunistic pathogen in specific-pathogen-free rabbits with the capability of cross-species transmission. Veterinary Microbiology, 2017, 201:72-77.
(10). Liu BY, Zhou EM, et al. Development of a blocking ELISA for detection of antibodies against avian hepatitis E virus. Journal of Virological Methods, 2014, 204:1-5.
5. Major research projects:
(1). National Natural Science Foundation of China, Antiviral mechanism of nanobodies against swine, rabbit and avian hepatitis E Virus, 2019-2021, 250,000 RMB Yuan, Program Leader;
(2). China Postdoctoral Science Foundation, Molecular mechanism of host factor CDC42 in the infection of genotype 4 swine hepatitis E virus, 2021-2023, 80,000 RMB Yuan, Program Leader;
(3). Natural Science Foundation of Shaanxi Province, Molecular mechanism and prevention of egg production decline caused by avian hepatitis E virus infection in laying hens, 2020-2021, 50,000 RMB Yuan, project leader;
(4). Chinese Universities Scientific Fund, Study on whole genome amplification and pathogenicity of hepatitis E virus from different animals, 2019-2022, 200,000 RMB Yuan, project leader.
(5) National Natural Science Foundation of China, Mechanism in infection, replication and pathogenicity of animal hepatitis E virus cross-species infection, 2018-2022, 2.3 Million RMB Yuan, participant.
6. Contact:
ADD: College of Veterinary Medicine, NWAFU, Xinong Road 22, Yangling, 712100, Shaanxi, China
Email: liubaoyuan0412@nwafu.edu.cn
TEL: 15109286126