LU zheng
LU Zheng
Ph.D., Lecturer.
Born in Nov. 1985, Chengde City, Hebei, China
Contact
Address: College of Veterinary Medicine, Northwest A&F University
No. 22 Xinong Road, Yangling, 712100, Shaanxi, China.
Email(s): luzheng@nwafu.edu.cn, lz_mixueer@163.com
Mobile: +86 13689246674
1. Education and Work Experience
07.2015 – now, Lecturer, College of Veterinary Medicine, Northwest A&F University
10.2016 – 06.2021, Postdoctoral training, College of Veterinary Medicine, Northwest A&F University
09.2010 – 06.2015, Ph.D., Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University
09.2006 – 06.2010, Bachelor, Veterinary Medicine, College of Veterinary Medicine, Hebei Normal University of Science and Technology
2. Research and Teaching
Research interests:
Role and mechanism of traditional Chinese veterinary medicine in porcine and poultry disease.
Teaching:
Veterinary Pharmacology, Veterinary Pharmacy and Natural Pharmaceutical Chemistry for bachelor students.
3. Memberships and Academic Services
Member of the Chinese Association of Veterinary Pharmacology
Member of the Chinese Association of Veterinary Microbiology
Editorial board member of Frontiers in pharmacology, Journal of Pharmacy and Pharmacology.
4. Publications
[1] Zheng Lu, Shengbo Cao, Hongbo Zhou, Ling Hua, Shishuo Zhang, Jiyue Cao*. Mechanism of Arctigenin-induced Specific Cytotoxicity Against Human Hepatocellular Carcinoma Cell Lines: Hep G2 and SMMC7721. PLOS ONE , 2015; 10(5): 1-16.
[2] Zheng Lu, Lingling Chang, Qian Du, Yong Huang, Xiaomin Zhang, Xingchen Wu, Jie Zhang, Ruizhen Li, Zelin Zhang, Wenlong Zhang, Xiaomin Zhao, Dewen Tong. Arctigenin Induces an Activation Response in Porcine Alveolar Macrophage Through TLR6-NOX2-MAPKs Signaling Pathway, Frontiers in pharmacology , 9 (2018) 475.
[3] Zheng Lu#, Lingling Chang#, Hongbo Zhou, Xiaoqiang Liu, Yinqian Li, Tiejun Mi, Dewen Tong. Arctigenin Attenuates Tumor Metastasis Through Inhibiting Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma via Suppressing GSK3beta-Dependent Wnt/beta-Catenin Signaling Pathway In Vivo and In Vitro, Frontiers in pharmacology , 10 (2019) 937.
[4] Zheng Lu, Hongbo Zhou, Shishuo Zhang, Wei Dai, Yan Zhang, Liping Hong, Fanjie Chen, Jiyue Cao. Activation of reactive oxygen species-mediated mitogenactivated protein kinases pathway regulates both extrinsic and intrinsic apoptosis induced by arctigenin in Hep G2, Journal of Pharmacy and Pharmacology , 72 (2020) 29-43.
[5] Zheng Lu, Bin He, Lijun Wu, Xiabing Chen, Jie Chen, Wenhai Yang, Zhiyong Shao, Sijiu Wang, Shengqiang Ye, Erguang Jin, Jiyue Cao. Optimisation of the conversion and extraction of arctigenin from Fructus arctii into arctiin using fungi, Frontiers in Microbiology , 2021, 12: 1062.
[6] Lingling Chang#, Zheng Lu#, Delong Li, Liang Zhang, Zhenyu Wang, Qian Du, Yong Huang, Xiaomin Zhao, Dewen Tong. Melamine causes male reproductive toxicity by destroying the blood-testis barrier in piglets, Toxicology Letters , 296 (2018):114-124.（Contribute equally）
[7] Shishuo Zhang, Wei Dai, Zheng Lu, Zhixin Lei, Bing Yang, Bin He, Hongbo Zhou, Jiyue Cao, Preparation and evaluation of cefquinome‐loaded gelatin microspheres and the pharmacokinetics in pigs, Journal of veterinary pharmacology and therapeutics , 2018, 41: 117-124.
[8] Li Zaijian, Zhang Weiyuan, Lu Xiaocong, Li Jing, He Bin, Jiang Hui, Wang Shasha, Lu Zheng, Wang Chunmei, Cao Jiyue*. Reaction temperature alters chorzoxazone metabolism in carp (Cyprinus carpio) hepatic microsomes. Fish Physiology and Biochemistry , 2012; 38(5): 1225-1231.
6. Projects and Funding
[1] Regulatory effects and mechanism of arctigenin on the immune function of 3D4/21 cells. General Project, No. 31602105, National Natural Science Foundation of China (NSFC), 200,000 RMB Yuan, 2017 - 2019, grant holder.
[2] Study on structural modification and antibacterial activity of natural product Arctigenin General Project, No. K3030122019, Natural Science Foundation of Shaanxi Province, 50,000 RMB Yuan, 2022 - 2023, grant holder.
[3] Immunoregulation of Intestinal mucosa in Piglets mediated by recombinant yeast. Key Project, No. 2021NY-027, Natural Science Foundation of Shaanxi Province, 200,000 RMB Yuan, 2020 - 2022, participant.
[4] The effect and mechanism of gene nik in the expression and transmission of gene mcr-1. General Project, No. 31702294, National Natural Science Foundation of China (NSFC), 260,000 RMB Yuan, 2018 - 2020, participant.
[5] The role and regulatory mechanism of gC1qR in inducing M2-type polarization of macrophages. General Project, No. 31672535, National Natural Science Foundation of China (NSFC), 610,000 RMB Yuan, 2017 - 2021, participant.