Title: Associate Prof. Xu, Xiaodong

　　Contact Information:

　　Mailing Address:

　　College of Life Sciences

　　Northwest A&F University

　　Yangling, Shaanxi 712100

　　P. R. China

　　Phone: (86) 15339264581

　　Fax:

　　E-mail: xuxd@nwsuaf.edu.cn <mailto:XXXXXXXX@nwsuaf.edu.cn>

　　Office: North Campus, Science Building, College of Life Sciences, D212

　　Research Interests:

　　1. Optimization of Baculovirus Expression Vector System (BEVS).

　　2. Virus encoded prion.

　　Education Experiences:

　　University of Reading, Virology, Ph.D. 2009

　　Beijing Agricultural University, Microbiology, M.S. 1995

　　Beijing Agricultural University, Microbiology, B. S. 1989

　　Professional Experiences:

　　Associate Professor in College of Life Science, Norwest A&F University (2009-present)

　　Technician in University of Reading, (2001-2009)

　　Honors and Awards:

　　Publications:

　　Liu H, Rahman SU, Mao Y, Xu X, Tao S. (2017) Codon usage bias in 5' terminal coding sequences reveals distinct enrichment of gene functions. Genomics. pii: S0888-7543(17)30065-4

　　Chen J, Xu X, Tao H, Wang Y, Chen H. (2016) Chemical shift assignments of nsp7α from porcine reproductive and respiratory syndrome virus. Biomol NMR Assign. 10(2):391-4.

　　Xu X, Zhou X, Nan H, Zhao Y, Bai Y, Ou Y, Chen H. (2016) Aggregation of AcMNPV LEF-10 and Its Impact on Viral Late Gene Expression. PLoS One. 11(5):e0154835. doi: 10.1371/journal.pone.0154835.

　　Liu L, Tian J, Nan H, Tian M, Li Y, Xu X, Huang B, Zhou E, Hiscox JA, Chen H. (2016) Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Protein Interacts with Nsp9 and Cellular DHX9 To Regulate Viral RNA Synthesis. J Virol. 90(11):5384-98.

　　Wang Y, Mao Y, Xu X, Tao S, Chen H. (2015) Codon Usage in Signal Sequences Affects Protein Expression and Secretion Using Baculovirus/Insect Cell Expression System.

　　PLoS One. 10(12):e0145887. doi: 10.1371/journal.pone.0145887

　　Wu F, Peng K, Tian J, Xu X, Zhou E, Chen H. (2014) Immune response to Fc tagged GP5 glycoproteins of porcine reproductive and respiratory syndrome virus. Viral Immunol. 27(7):343-9.

　　Liu B, Wang R, Wu F, Xu X, Chen H. (2014) Rapid production of HIV-1 neutralizing antibodies in baculovirus infected insect cells. Protein Expr Purif. 99:87-93.

　　Xu X, Chen Y, Zhao Y, Liu X, Dong B, Jones IM, Chen H. (2013) Baculovirus superinfection: a probable restriction factor on the surface display of proteins for library screening. PLoS One. 8(1):e54631. doi: 10.1371/journal.pone.0054631

　　Porta C, Xu X, Loureiro S, Paramasivam S, Ren J, Al-Khalil T, Burman A, Jackson T, Belsham GJ, Curry S, Lomonossoff GP, Parida S, Paton D, Li Y, Wilsden G, Ferris N, Owens R, Kotecha A, Fry E, Stuart DI, Charleston B, Jones IM. (2013) Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity. J Virol Methods. 187:406-12

　　Kong L, Sheppard NC, Stewart-Jones GB, Robson CL, Chen H, Xu X, Krashias G, Bonomelli C, Scanlan CN, Kwong PD, Jeffs SA, Jones IM, Sattentau QJ. (2010) Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity. J Mol Biol. 15:131-47

　　Chen H, Xu X, Lin HH, Chen SH, Forsman A, Chapman MA, Jones IM. (2008) The immune response to the outer domain of a HIV-1 clade C gp120 is predominantly V3 specific and includes neutralising antibodies. J. Gen. Virol. 89:2597－2604

　　Mathewson AC, Bishop A, Yao Y, Kemp F, Ren J, Chen H, Xu X, Berkhout B, van der Hoek L, Jones IM. (2008) Interaction of severe acute respiratory syndrome-coronavirus and NL63 coronavirus spike proteins with angiotensin converting enzyme-2. J. Gen. Virol. 89:2741-2745

　　Chen H, Xu X, Jones IM. (2007) Immunogenicity of the outer domain of a HIV-1 clade C gp120. Retrovirology 4:33

　　Chen H, Xu X, Bishop A, Jones IM. (2005) Reintroduction of the 2G12 epitope in an HIV-1 clade C gp120. AIDS 19(8):833-835

　　Xu X, Jones IM. (2004) Rapid parallel expression in E. Coli and insect cells: analysis of five lef gene products of the Autographa californica multiple nuclear polyhedrosis virus (AcMNPV). Virus Genes. 29(2):191-197

　　Tan Z, Xu X, and Chen W. (1997) Phylogenetic and Genetic Relationships of Mesorhizobium tianshanense and Related Rhizobia. Int. J. Syst. Bacteriol. 47(3):874-879