关于举办“蛋白质代谢与肿瘤”学术报告的通知
报告题目:(1)“蛋白质代谢与肿瘤”
(2)“Graduate Study, the Bridge to a Successful Scientific Career----通向成功科学之路的桥梁”
报 告 人:李晓涛 华东师范大学特聘教授;
美国贝勒医学院客座教授
报告时间:2010年6月22日下午16:00
报告地点:生命学院四层多媒体教室
报告人简历:
EDUCATION
2001 Graduate School of Biomedical Sciences (Ph. D.)
Program of Genes and Development
Department of Biochemistry and Molecular Biology
UT M.D. Anderson Cancer Center
1995 Graduate School of Biomedical Sciences (M. S.)
Program of Microbiology and Molecular Genetics;
The University of Texas Health Science Center, Houston
1989 Chongqing University of Medical Sciences
Chongqing, China (M. D.)
WORKING EXPERIENCE
Sept 2008-Current Adjunct Faculty, Baylor College of Medicine, Houston, TX
Aug 2007-Current Professor, East China Normal University, Shanghai
Jul, 2006 to Jul 2007 Assistant Professor, Baylor College of Medicine
2005-06 Instructor, Baylor College of Medicine
2001-05 Postdoctoral associate in Dr. Bert O’Malley’s laboratory
1995-01 Graduate Research Assistant,with Dr. Willian Klein.
Department of Biochemistry and Molecular Biology
UT M.D. Anderson Cancer Center
1989-92 Physician (Internal medicine and Infectious Diseases)
The First Associated Hospital
Chongqing University of Medical Sciences
PUBLICATIONS (*corresponding author)
1. Guang Gao, Jerry Wong, Jingchun Zhang, Ivy Mao, Jayant Shravah, Ping Zhou, Allen
Xiao, Li X *, Honglin Luo Proteasome Activator REG? Enhances Coxsackieviral Infection via
Facilitating p53 Degradation. J. Virology. In revision.
2. Liu J, Yu G., Zhao P., Wang C., Luo H., Long W., Wang Y., Zhao Y., Tsai M.,O’Malley B.W. and Li X*. REGγ
modulates p53 activity by regulating its cellularlocalization. J. Cell Science. In revision.
3. Yu G, Zhao Y, He J, Mukherjee A, Mao CA, Li M, and Li X*. Comparative analysis of
REGγ expression augurs functional implication. J. Mol. Cell. Biol. In press.
4. Ivy Mao, Jian Liu, Li X*, Honglin Luo. REG?, A Proteasome Activator and Beyond?
Cell and Mol Life Sci. 2008 Dec;65(24):3971-80.
5. Li X, Larbi Amazit, Weiweng Long, David M. Lonard, John J. Monaco and
O’Malley B.W. Proteolytic turnover of p21 by the REGgamma-proteasome
pathway. (2007)(Mol. Cell, 26, 831-842)
6. Li X., Lonard D., Jung S.Y., Malovannaya A., Feng Q., Qin J., Tsai S. Y., Tsai M-J., and O’Malley B.W.
The SRC-3/AIB1 coactivator is degraded in an ubiquitin- and
ATP-independent manner by the REG?-proteasome (2006) Cell. 124, 381-392.
7. Verma S., Ismail A., Gao X., Fu G., Li X., O’Malley B. W., Nawaz Z. Ubiquitin-conjugating
enzyme, UBCH7 act as a coactivator for steroid hormone receptors. (2004) Mol.Cell. Biol. 24, 8716-26.
8. Li X. Lonard D. M. and O’Malley B. W. A Contemporary Understanding of
Progesterone Receptor Function (Review). (2004) Mechanisms of Aging and Development. 125,669-78.
9. Auboeuf D., Dowhan D.H., Li X., Larkin K., Ko L., Berget S.M., O’Malley B.W. CoAA,a Nuclear Receptor
Coactivator Protein at the Interface of Transcriptional Coactivation
and RNA Splicing. (2004). Mol. Cell. Biol. 24, 442-53.
10. Li X. and O’Malley B.W. Unfolding the action of progesterone
receptors(minireview). (2003). J. Biol. Chem. 10, 39261-4.
欢迎相关专业的教职员工、研究生届时光临!
生命科学学院
2010年6月21日